pentobarbital will minimize the extent or result of trazodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will minimize the extent or effect of meloxicam by influencing hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Unknown.
Reserve concomitant prescribing of such drugs in individuals for whom other remedy possibilities are inadequate. Restrict dosages and durations into the bare minimum required. Keep an eye on closely for indications of respiratory depression and sedation.
Comment: Barbiturates could enhance adverse effects, such as respiratory depression, made by harmful doses of TCAs. With therapeutic doses of TCAs, barbiturates increase metabolism and reduce blood concentrations of TCAs.
pentobarbital will lessen the level or influence of levamlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or outcome of irinotecan liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
With therapeutic doses of TCAs, barbiturates boost here metabolism and decrease blood concentrations of TCAs.
pentobarbital decreases levels of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral sort of equally agents. Small/Importance Mysterious.
pentobarbital will lessen the level or effect of piroxicam by affecting hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Unidentified.
pentobarbital will lessen the level or influence of celecoxib by affecting hepatic enzyme CYP2C9/ten metabolism. Minimal/Significance Unknown.
fentanyl transmucosal and pentobarbital each improve sedation. Avoid or Use Alternate Drug. Limit use to patients for whom different treatment alternatives are insufficient
Keep an eye on Closely (1)pentobarbital will lower the extent or outcome of glecaprevir/pibrentasvir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Potential for false optimistic examination final results if macimorelin and strong CYP3A4 inducers are coadministered. Discontinue strong CYP3A4 inducer, letting for enough washout time, prior to testing.
pentobarbital will decrease the level or impact of voriconazole by affecting hepatic enzyme CYP2C9/ten metabolism. Insignificant/Significance Not known.